Adenosine A2 Receptor: Key To Understanding Cardiovascular, Pain and Sleep-Wake Cycle Regulations
Adenosine A2 Receptor: Key To Understanding Cardiovascular, Pain and Sleep-Wake Cycle Regulations
Adenosine A2 receptor (A2R) is a G protein-coupled receptor that is expressed in various tissues and cells throughout the body. It is a key mediator of physiological processes such as inflammation, pain, and sleep-wake cycle. The A2R receptor has four different subtypes, A2R1, A2R2, A2R3, and A2R4, which are expressed in different tissues and cell types.
Adenosine A2 receptor (A2R) is a G protein-coupled receptor that is expressed in various tissues and cells throughout the body. It is a key mediator of physiological processes such as inflammation, pain, and sleep-wake cycle. The A2R receptor has four different subtypes, A2R1, A2R2, A2R3, and A2R4, which are expressed in different tissues and cell types.
A2R1 is the most abundant subtype and is expressed in the heart, skeletal muscles, and the central nervous system (CNS). It is involved in the regulation of cardiovascular function, including heart rate and contractions, and has been implicated in the development of cardiovascular disease.
A2R2 is expressed in the lungs, eyes, and CNS and is involved in the regulation of airway regulation and blood pressure. It has been shown to have anti-inflammatory effects and may be a potential therapeutic target for chronic obstructive pulmonary disease (COPD).
A2R3 is expressed in the kidneys and is involved in the regulation of renal function. It has been shown to have anti-inflammatory effects and may be a potential therapeutic target for chronic kidney disease.
A2R4 is the least abundant subtype and is expressed in the brain, where it is involved in the regulation of neurotransmitter release and behavior. It has been shown to have anti-inflammatory effects and may be a potential therapeutic target for depression and anxiety disorders.
The A2R receptor is a G protein-coupled receptor, which means it is composed of a transmembrane protein that is connected to a intracellular signaling pathway. This pathway involves the regulation of various cellular processes, including intracellular signaling, cell signaling, and inflammation.
The A2R receptor is involved in the regulation of several physiological processes, including cardiovascular function, pain perception, and sleep-wake cycle. It is also involved in the regulation of neurotransmitter release and behavior.
A2R1 is involved in the regulation of cardiovascular function, including heart rate and contractions. It has been shown to increase heart rate in response to exercise and to decrease heart rate in response to rest. A2R1 may also be involved in the regulation of blood pressure and blood flow.
A2R2 is involved in the regulation of airway regulation and blood pressure. It has been shown to increase airway resistance in response to exercise and to decrease blood pressure in response to stress. A2R2 may also be involved in the regulation of pain perception and the regulation of neurotransmitter release.
A2R3 is involved in the regulation of renal function. It has been shown to increase urine output in response to exercise and to decrease urine output in response to stress. A2R3 may also be involved in the regulation of pain perception and the regulation of neurotransmitter release.
A2R4 is involved in the regulation of neurotransmitter release and behavior. It has been shown to increase neurotransmitter release in response to exercise and to decrease neurotransmitter release in response to stress. A2R4 may also be involved in the regulation of pain perception and the regulation of neurotransmitter release.
The A2R receptor is a potential drug target for several diseases, including cardiovascular disease, chronic obstructive pulmonary disease (COPD),
Protein Name: Adenosine A2 Receptor (nonspecified Subtype)
More Common Targets
Adenosine deaminase | Adenosine receptor | Adenylate Cyclase | ADGB | ADGB-DT | ADGRA1 | ADGRA2 | ADGRA3 | ADGRB1 | ADGRB2 | ADGRB3 | ADGRB3-DT | ADGRD1 | ADGRD2 | ADGRE1 | ADGRE2 | ADGRE3 | ADGRE4P | ADGRE5 | ADGRF1 | ADGRF2 | ADGRF3 | ADGRF4 | ADGRF5 | ADGRG1 | ADGRG2 | ADGRG3 | ADGRG4 | ADGRG5 | ADGRG6 | ADGRG7 | ADGRL1 | ADGRL1-AS1 | ADGRL2 | ADGRL3 | ADGRL4 | ADGRV1 | ADH1A | ADH1B | ADH1C | ADH4 | ADH5 | ADH5P4 | ADH6 | ADH7 | Adhesion G-protein coupled receptor G1 (isoform a) | ADHFE1 | ADI1 | ADIG | ADIPOQ | ADIPOQ-AS1 | ADIPOR1 | ADIPOR2 | ADIRF | ADK | ADM | ADM-DT | ADM2 | ADM5 | ADNP | ADNP2 | ADO | ADORA1 | ADORA2A | ADORA2A-AS1 | ADORA2B | ADORA3 | ADP-Ribosylation Factor | ADPGK | ADPGK-AS1 | ADPRH | ADPRHL1 | ADPRM | ADPRS | ADRA1A | ADRA1B | ADRA1D | ADRA2A | ADRA2B | ADRA2C | ADRB1 | ADRB2 | ADRB3 | Adrenoceptor | Adrenomedullin receptor 1 | Adrenomedullin receptor 2 | ADRM1 | ADSL | ADSS1 | ADSS2 | ADTRP | AEBP1 | AEBP2 | AEN | AFAP1 | AFAP1-AS1 | AFAP1L1 | AFAP1L2 | AFDN | AFDN-DT